Question 1: [total 40 marks] Read the article Koutsky et al 2007 and briefly answer the following questions: State the research question the authors plan to answer. Hint use PICO. [4 marks] Identify the type of study design used in this study. [2 marks] Randomized Case control study List at least two key characteristics of this study design? [2 mark] What was the source population for this research trial? [2 mark] Identify the inclusion criteria applied to the study population. [2 marks] Identify the interventions given to the people in the treatment group and the control group. [2 marks] Identify the primary outcome/s or dependent variable/s for this study. [2 mark] The next 3 questions ask you to briefly list the characteristics, and provide some examples, if relevant, you would consider when appraising a research study, such as Koutsky et al 2007. Question 1.8 focuses on how to determine if the study is relevant or generalisable (or externally valid) to your clinical practice, or, your research question. What characteristics of the study do you consider to determine if it is generalisable? List or describe factors related to generalisability [4 marks] Discuss generalisability specifically in relation to Koutsky et al 2007 [4 marks] Question 1.9 focuses on how to determine the importance of the findings...for this question, focus on the internal validity of the study. What characteristics of this type of study design will you consider to determine if its findings are valid? List or describe factors related to internal validity [4 marks] Discuss internal validity specifically in relation to Koutsky et al 2007 [4 marks] Question 1.10 focuses on how to determine the clinical significance and statistical significance of the reported measures of effect. ...
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