CASE SCENARIO FOR THE LABORATORY REPORT
XXXXXXXXXXAgo: 57)
00s:
7
Gender:
‘specimen Type:
AC LEFT BREAST
Clinical Details:
0 6 mm, Disiance from ripple 48 mm. Coordinates 5
Left Mass-poorty defined. Si
FoF on size 6 mm. Multifocal lobe. Axila normal.
Macroscopic Description:
A LEFT BREAST:
EE issue measuring 15,15 and 14mm erg
‘AT Fa. Breast core protocol. All taken.
Microscopic Descri
oe mopey nfilated by grade 2 invasive ductal carcinoma with focal high grade DCIS
eceptors o follow.
Hormone Receptors:
ER: Alred Score 818
PR: Allred Score 418,
HER?: Score 2+, FISH a!
R2 (ERBB2) Gene Amplification
Weak Posiive (weak staining in 20% of tumour ces)
waited
FISH Testing - HE
Tissue Type: Breast
20 Tumour Calls Assesse
HER2/CEP17 Ratio: 1.13
Mean CEP17/Cell: 2.00
Mean HER2 Gene/Cell: 2.25
Rosult: HER2 Gene is NEGATIVE
d (BioView)
ctal carcinoma. BS
Final Diagnosi
Left
east, core biopsy: - IMV2SH® du
Questions to be answered:
1
SBU
criteria required for specimen
EST1892
dent the patient dentifrs and discuss the.
acceptance.
Drecuss the importance of cinical information in this case.
Discuss the importance of screening programmes in tis cas:
and why do they exist?
Explain the hormone receptors res
Whats the significance of HER? for tis patient?
What other tests/ICC that can be used for
east cancer diagnosis?
What would be the suggested treatment considering the results?
what does it involved
including HER?.