Genetic linkage mapping for a large number of families identifies 4% recombination between the genes...

Question

Genetic linkage mapping for a large number of families identifies 4% recombination between the genes for Rh blood type and elliptocytosis. At the Rh locus, alleles R and r control Rh+ and Rh- blood types. Allele E producing elliptocytosis is dominant to the wild-type recessive allele e. Tom and Terri each have elliptocytosis, and each is Rh+. Tom's mother has elliptocytosis and is Rh- while his father is healthy and has Rh+. Terri's father is Rh+ and has elliptocytosis; Terri's mother is Rh- and is healthy.

What is the probability that the first child of Tom and Terri will be Rh- and have elliptocytosis?

Robert · Accepted Answer

The alleles for the RH blood type(R for Rh+ and r for Rh-) and the alleles for elliptocytosis (E 
for those who are suffering from the disease and e for those who are healthy) are linked on the 
same chromosome.  Since the percent recombination is four percent the two linked genes are 4 
cm apart.

Genetic linkage mapping for a large number of families identifies 4% recombination between the genes for Rh blood type and elliptocytosis. At the Rh locus, alleles R and r control Rh+ and Rh- blood...

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