Hi,This experiment is about Preparation of Aspirin and I would like from you to write a report.The...

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Hi,This experiment is about Preparation of Aspirin and I would like from you to write a report.The report should be up to 700 words and it should include: abstract, introduction, materials and methods, results and discussion. All of them should be written in paragraphs and the method should not be copied exactely from the instruction. If you use any reference, please, write the complete reference in the end.Please, it is very important to avoid plagiarism.

Robert · Accepted Answer

ONE STEP PREPARATION OF THE ANALGESIC- ASPIRIN AND  ITS 
PRECURSOR SALICYLIC ACID  
ABSTRACT:  
Acetyl salicylic acid or aspirin 1 is chemically an aromatic carboxylic 
acid, which also contain an ester group in its ortho position. It is popular 
counter top medicinal preparation used for the effective management of 
minor pains, cold, fever, minor inflammations etc. It can be used to bring 
down fever.  This chemical can be synthesised in a to check the our single 
step  by the reaction  salicylic acid with acetic anhydride in presence of 
sulphuric acid. The amount of the compound formed depends on the 
amount of salicylic acid taken. It can be compared to the theoretical yield. 
Melting point is also determined to check the purity of the product. Salicylic 
acid, which is the starting material of aspirin, can be prepared from methyl 
salicylate by alkaline hydrolysis in a single step. Methyl salicylate is a 
phenolic ester while salicylic acid is a phenolic acid. The yield and melting 
point of this compound is also reported. 2 
INTRODUCTION 
1. One step synthesis of Aspirin from Salicylic Acid 
There are many methods to synthesis salicylic acid, but the best and 
easy method is from salicylic acid. Salicylic acid is 2-hydroxybenzoic acid. 
Industrially is prepared by the carboxylation of phenol in presence of an 
alkali using Kolbe – Schmidt reaction.  
This can be acetylated using acetic anhydride in presence of 
concentrated sulphuric acid to form aspirin. Acetic anhydride acts as the 
source of acetyl group. Concentrated sulphuric acid helps I the removal of 
acetic acid and hence acts as a catalyst. The overall reaction is an 
esterification reaction.3
                                                           
1 http://www.aspirin.com/scripts/pages/en/aspirin_history/index.php 
2 Aspirin retrieved from http://en.wikipedia.org/wiki/Aspirin 
3 Salicylic Acid retrieved from http://en.wikipedia.

Hi,This experiment is about Preparation of Aspirin and I would like from you to write a report.The report should be up to 700 words and it should include: abstract, introduction, materials and...

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