Using the MidTerm, determine HQ and risk, as appropriate, for each chemical and each pathway.Risk =...

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Using the MidTerm, determine HQ and risk, as appropriate, for each chemical and each pathway.Risk = toxicity x ExposureHQ (Hazard quotient) = E/RfD E = Exposure intakeRfD = reference dose(E andRfD must be in same units)
	
Document Preview: Given Data TableAirGroundwaterSoilChemicalMax, mg/m3Max, mg/LMax, mg/kgChlorobenzene8.09e-81.10e-26.40Chloroform3.12e-127.60e-34.101,2-Dichloroethane2.40e-82.00e-32.2BEHP8.29e-7.0102.30e2BEHP-bis-2-ethyl hexyl phthalate (on RBC Table listed under “phthalates“)1. For each compound, determine if the maximum concentration is above USEPA RBC screening values.AnswerAs per USEPA RBC screening Value, AirGroundwaterSoilChemicalMax, mg/m3Max, mg/LMax, mg/kgChlorobenzene5.2e+25.3e-22.8e+2Chloroform1.2e-16.1e-53.2e-11,2-Dichloroethane1.87.8e-44.6e-1BEHP1.21.33.9e+1As per the above table we can see that, 1,2 di-chloro ethane is above the screening level in ground water and soil and BEHP is above careening value in soil. 2. Determine the daily intake for all compounds listed in Table 1 from dermal contact of soils by residents. Note that some chemicals may require evaluation as both carcinogens and non-carcinogens.AnswerExposure factor for 0-1 years and 1-11 are 0.09 and 0.91 respectively. That can be calculated as follows,EF = (F x ED) / ATEF = (365*1) / (11 x 365)EF = 0.09Similarly, for 1-11 age years EF = 0.91Now dose can be calculated as, D = Exposure for 0-1 and Exposure for 1-11D = [(C x A x AF x EF x CF) / BW] + [(C x A x AF x EF x CF) / BW]Here D is Daily Intake, C is concentration of Contaminant in mg/kgEF = exposure Factor, 0.9 and 0.91BW = body weightCF = Conversion factor, 10-6A = Total Soil adhered = 210, 525AF = Bioavailability factor, 0.1Using the above formula, we can calculate the Daily dose of residents by exposure to soil as,ChemicalAirGround WaterSoilDaily IntakeChlorobenzene8.09E-081.10E-026.41.14016E-05Chloroform3.12E-127.60E-034.17.30415E-061,2-Dichloroethane2.40E-082.00E-032.23.9193E-06BEHP8.29E-070.012.30E+02 XXXXXXXXXX3. Determine the daily intake for all compounds listed in Table 1 from...

Robert · Accepted Answer

Air HQ Risk Groundwater HQ Risk Soil HQ Risk 
Chemical  Max, 
mg/m3 
   Max, 
mg/L 
   Max, 
mg/kg
Chlorobenzene  5.2e+2 =(5.2E+2/2E-
2) =2.6E4 
=(5.2e+2*2E-
1) 
=104 
 5.3e-2 = (5.3E-
2/2E-2)  
=2.65 
=(5.3E-
2*2E-1) 
=0.0106 
 2.8e+2 =(2.8E2/2E-2) 
=1.4E4 
=(2.

Using the MidTerm, determine HQ and risk, as appropriate, for each chemical and each pathway. Risk = toxicity x Exposure HQ (Hazard quotient) = E/RfD E = Exposure intake RfD = reference dose (E andRfD...

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