1. 1. Suppose that the true exposure status is 150 smokers among the cases and 100 smokers among the controls. What is the true crude OR?
2. 2. What would be the observed OR using the serum thiocyanate measure for smoking status with a sensitivity of 86 percent and specificity of 79 percent?
3. 3. So far we have been considering how the observed OR may be different from the true OR under conditions of an imperfect test to measure exposure. How might we do the opposite—adjust the observed OR to the true OR, taking into consideration the characteristics of the test of exposure?
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