Great Deal! Get Instant $10 FREE in Account on First Order + 10% Cashback on Every Order Order Now

ox Nepali Calendar, Nepali Ca X | © CAMPUS FEED X | 9 BIOL XXXXXXXXXXSemester 2 = X @ David_STUDENT_version_ X @ David_STUDENT_version_ X | & https://www.unifolks.com/s X | + v & > Ca...

1 answer below »
ox Nepali Calendar, Nepali Ca X | © CAMPUS FEED X | 9 BIOL XXXXXXXXXXSemester 2 = X @ David_STUDENT_version_ X @ David_STUDENT_version_ X | & https:
www.unifolks.com/s X | + v

& > Ca leo.acu.edu.au/pluginfile.php/5587385/mod_page/content/63/David_STUDENT_version_202260.pdf a fh ww 0O [« } :
= David_STUDENT_version_202260.pdf il — 83% + [EE LA
BIOL121 ASSIGNMENT 3: Written assessment
Scenario: David
David is a 41-year-old male, who has made an appointment to see his GP for his biannual health check. He
tells the doctor that he has been feeling “a bit puffed” walking around the course during his weekly game of
golf and that he seems to be urinating more frequently of late. David reports he has gained nine kilos since
his 30th birthday, and his waist measurement has expanded. He laughs this off as “middle-aged spread” and
says his wife tells him he needs to watch what he eats and drink less alcohol. David works as a software
engineer, which he has been finding very stressful of late, and spends a lot of his time in the office sitting in
front of a computer, snacking on his favourite salt and vinegar chips. David and his wife are keen to start a
family but have not yet been successful in conceiving.
On the advice of his doctor, David has been taking aspirin in the evenings for the past 18 months to lower his
isk of heart attack and Zocor® to address cholesterol.
Physical examination:
Blood work Blood type = O*
Blood glucose = 10 mmol/L
Blood Testosterone levels = 154 ng/dL
GnRH = low
155/99 mm Hg
IE
Mostly healthy meals. Snacks on high
fat & sugar, processed foods. Heavy
alcohol consumption.
months. Cholesterol levels have been
high at the last three check-ups. Takes
Aspirin in the evenings. Gall bladde
emoved 5 years ago.

[Leukocytes ~~ [- |
Answered 1 days After Oct 21, 2022

Solution

Dr Insiyah R. answered on Oct 22 2022
49 Votes
Topic-1 Reproduction    1
Topic 2- Respiratory system    2
Topic 3- Digestive system    3
Topic 4- Pharmecology    4
Refrence    5
Topic-1 Reproduction
David, a 41-year-old man, has scheduled his biannual checkup with his doctor. He admits to feeling "a little puffed" when walking around the golf course during his weekly round of golf and has recently noticed a recent increase in the frequency of urination to the doctor.
A decrease in testosterone level, glandular and seminal vesicle weights and the number of sperm are all linked to hypercholesterolemia and hypertriglyceridemia (Ellinger & Chatuphonprasert,2022). A few years later, Zhu et al, (2019) showed that a high-energy diet (HED) had no effect on sperm concentration or viability but did increase the amount of sperm with abe
ant morphological and sperm motility. The secretory function of Leydig and Sertoli cells, spermatogenesis, the sperm cytoskeleton, the epididymal sperm maturation process, and sperm fertilising ability were all negatively affected by hypercholesterolemia caused by a high-cholesterol diet in a model (Zhu et al,2019). It has also caused a drop in fertility index, sperm concentration, motility, viability, testicular weight, degenerative changes in the testicles, atrophy of the seminiferous tubules, and a stop to sperm production (Ellinger & Chatuphonprasert,2022). Ejaculate volume, sperm count, and motility were all negatively affected by hypercholesterolemia, and sperm morphological defects, especially abe
ant sperm heads and the presence of cytoplasmic droplets, were up.
Steroid hormones, mostly generated from cholesterol, make up the bulk of a person's sexual hormones. As a result, cholesterol is essential for the physiology of male and female reproduction, beginning with sex differentiation and ending with the creation of gametes (Ellinger & Chatuphonprasert,2022). Numerous research has been done to find out how HED and hypercholesterolemia affect the hormones men need for reproduction. Some of the hormones evaluated in those studies shared findings consistently with others.
Damage to cells may result from oxidative stress, which is defined as an imbalance between reactive oxygen species production and antioxidant-ca
ying capacity. Normal sperm activities, including capacitation, acrosomal response, hyperactivation, motility, sperm-oocyte adhesion, and fertilisation, need low reactive oxygen species (ROS) levels (Ellinger & Chatuphonprasert,2022). However, oxidative stress is particularly harmful to sperm because it may set off an apoptotic cascade, resulting in the death of the cell and the loss of motility, DNA integrity, and vitality. Polyunsaturated fatty acid concentrations in the sperm mem
ane are high, while antioxidant enzyme levels in the cytoplasm are low, leaving the sperm vulnerable to damage.
Men's reproductive health and sperm shape are directly tied to the metabolism of fatty acids. Reduced spermatogenesis occurs when this process is impaired. During spermatogenesis, the testes rely on their dynamic lipid metabolism to stabilise the fatty acid rea
angement. Researchers discovered that fatty acid synthase and sterol response element interaction protein-1 c (srebp1c) mRNA levels were lower in double LXR...
SOLUTION.PDF

Answer To This Question Is Available To Download

Related Questions & Answers

More Questions »

Submit New Assignment

Copy and Paste Your Assignment Here