Solution
Abhinaba answered on
Aug 26 2021
Running Head: WOUND INFECTION AND HEALING
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WOUND INFECTION AND HEALING
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WOUND INFECTION AND HEALING
Table of Contents
4WOUND INFECTION
4Systemic Factors
4WOUND HEALING PROCESS
5Rapid Haemostasis
5Inflammatory Phase
5Proliferative Phase
5Remodelling phase
6MOIST WOUND HEALING
6ASEPTIC NON-TOUCH TECHNIQUE (ANTT)
8References
Wound Infection
Infected wound refers to a localized defect or
each in the skin integrity which favours cascade of processes step by step. The various steps involved are (i) exposure of underlying tissue and, (ii) microbial colonisation and proliferation in the presence of optimum moisture, temperature and nutritive conditions (iii) formation of biofilms involving consortia of bacteria, fungi and viruses (iv) inflammation of the targeted tissue (iv) delayed healing process.
Systemic Factors
The systemic factors involved are age (aging population serves a major risk), gender and sex hormones (males are prone to more risk as compared to females because estrogens hormone in females negatively impacts the healing of wounds by controlling different genes particularly associated with inflammation) (Yuan, Foushee, Johnson, Jockheck-Clark & Stahl, 2018). Nutrition and stress which causes diseases like diabetes, cardiovascular problems, immune compromised conditions contributing to more adverse conditions (Slater, 2008).
Wound Healing Process
The loss of skin in wound infection, if neglected, then it paves way multiple organ dysfunction syndromes, for a systemic infection, and sepsis, which could be fatal. Therefore, wound healing is necessary to avoid any complications later on. Wound healing helps in protecting the exposed area of the body and reduces the scope of infection and is therefore, a vital process consisting of planned steps occu
ing in a specific and governed way (Guo & DiPietro, 2010). The events involved are discussed as follows:
Rapid Haemostasis
Rapid Haemostasis starts immediately after the injury takes place with shrinkage in the blood vessels followed by blood clotting; these processes, further result into the secretion of pro-inflammatory cytokines and growth factors such as platelet-derived growth factor (PDGF), transforming growth factor (TGF)-β, epidermal growth factor (EGF) and fi
oblast growth factor (FGF) (Dugan et al., 2019).
Inflammatory Phase
After clotting, inflammatory cells move towards wound by a mechanism called chemotaxis which is denoted by the invasion of engulfing cells like neutrophils, macrophages and T-lymphocytes. Neutrophils act against the wound causing organisms by producing reactive oxygen species (Leaper, Assadian &...