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Running Head: ADAPTIVE PLATFORM TRIALS    1
ADAPTIVE PLATFORM TRIALS         8
ADAPTIVE PLATFORM TRIALS
Q1.
The distinguishing features of RCTs include random allocation of participants to the group, strict inclusion and exclusion criteria, blinding of evaluators and participants, a control group against which the intervention is tested and the standardization of the study protocol. As the RCT or the randomized controlled trial is considered as an experimental form of impact evaluation in which the population who are receiving the program or the policy intervention is chosen randomly from the eligible population. The distinguishing features of the traditional RCTs imply what are the factors that are considerably distinct from the subjected factors.
    There are certain pros and cons of the traditional RCTs. Prime pros of the Traditional RCTs include-
Comparative
In the traditional RCT one treatment is directly compared to another in order to establish the superiority. It is also very useful in making the strongest empirical evidence of a treatment efficacy.
Minimizes Bias
The traditional RCT helps in minimizing the allocation bias and the selection bias.
Minimizes Confounding Factors
The traditional RCT also helps in the minimization of confounding due to the unequal distribution of the prognostic factors. The advantages of this factor relies as the main thing it constitutes is to make the group utter comparable in context of the data it has collected through the several known and unknown sources, which was found by the investigators during research.
To Control the Exposure Events
Another pro of the RCTs is it helps the researchers in accessing and getting control over the several related events. This is the prime advantage that the researchers have as it helps them in controlling the results.
Cons
Some Randomization Efforts may be Predictable
The prime disadvantages of the traditional RCT is some of the randomized control methods use block methods to selects participants for a research project. This advantage can possibly results in higher level of the selection bias that is not considered good in the study groups.
Ethical Limitations
Some of another disadvantages related to the traditional RCT is in this method several prime ethical limitations are associated as certain level of clinical equipoise is required in the active randomization. The biggest disadvantage is the investigators cannot ethically provide random groups of patients their treatment options unless both the selection has an equal level of support.
The Data does not Show the Critical Information’s needed for Results
Another disadvantage of the RCT method is the data does not primarily showcases the critical information needed for the result. It sometimes influences the overall outcomes of the report.
Q2.
The primary ways in which the adaptive platform trials differ from a RCT includes-
The most prime thing that...