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Provide a summary (>250 words) for the below article by describing what key design features, what challenges to tackle for bioreactor design for viral vaccine production, what advantages of the...

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Provide a summary (>250 words) for the below article by describing what key design features, what challenges to tackle for bioreactor design for viral vaccine production, what advantages of the proposed bioreactor, etc. Berrie et al. 2020. “Development of a high-yield live-virus vaccine production platform using a novel fixed-bed bioreactor”. Vaccine, 38, XXXXXXXXXX.
Answered Same Day Sep 20, 2022

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Dr. Saloni answered on Sep 20 2022
67 Votes
1
Summary
Vero cells are among the most widely used adherent cell lines for the manufacturing of viral vaccines. However, because of the logistical constraints encompassing adherent cell line mechanisms, including heavy equipment footprints, labor-intensive procedures, and time and higher costs per dosage, production is constrained. Researchers resolved this limitation by developing a viral vaccine production programme based on the unique single-use scale-XTM ca
o bioreactor. The authors introduce a new bioreactor system that enables a cost-effective and scalable method for the production of viral vaccines. These bioreactors integrate a flatware system's low shear atmosphere...
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