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Patient details: Female (XX), Juliet Capule A tumour was detected in Ms Capulet as part of routine mammogram screening DOB: 23rd December, 1947 Breast cancer stage: localised, Grade I, 3cm...

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Patient details:
Female (XX), Juliet Capule   
A tumour was detected in Ms Capulet as part of routine mammogram screening
DOB: 23rd December, 1947
Breast cancer stage: localised, Grade I, 3cm
Immunohistochemistry result: ER positive and PR positive in 100% 0f cells, HER2 negative, low Ki67
1) What are the likely psycho-social impacts of this diagnosis for this patient?
 
2) What is the average prognosis for (i) 5-year and (ii) 10-year survival for patients diagnosed with a tumour having these characteristics? How does prognosis change if the cancer has already spread at diagnosis – compare 5 positive lymph nodes versus 10 positive lymph nodes.
 
3) Does the patient’s age affect her prognosis for survival?
 
4) Describe the likely appearance and distribution of the patient’s tumour in her body
 
5) Based on the immunohistochemistry results, what targeted therapies would you recommend for this patient?
 
6) What do the Ki67 and mitotic indices tell you about the biology of the tumour cells?
details-22urawuv-mkfeod3u.docx
Answered 6 days After May 04, 2021

Solution

Sumita Mitra answered on May 07 2021
146 Votes
5
Answers:
1) In this case the psycho social impact for this patient would be in a way which can affect the life of not the patient alone but also the family members and close relatives. The common reactions that can be seen are the ones of shock and denial and non-acceptance of the diagnosis and can also lead to depression, anger and anxiety. In her case here she is diagnosed with level 1 cancer and also a tumour being diagnosed, she is supposed to have negative mood and emotions of grief with
ief periods of calmness. (Nail,2001). That is the reason why, such people need a good support system in terms of family, friends and close relatives.
2) The prognosis is affected by many factors like the type of the cancer and the part in which it is affected in the body and also the stage of the same with its spread and impact and also the type and size of the tumour, if any. In many cases it is seen cancer remains in the body cells and come back with five years. In the case of
east cancer like her there are chances of that spreading to other parts of the body and become critical. The average 5-year survival rate for women with non-metastatic invasive
east cancer is 90% and it is seen to be around 84% for 10 years’ survival rate. In case of her she is diagnosed with the cancer in the
east so the five-year survival rate is around 99%. The prognosis changes when the cancer spread internally because the cancer has metastasized, which means that the spread of the cancerous cells has gone...
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