Hello I need help with my EBP paper i attached my paper the part i have done and you will just add the analysis of literature part from the articles in the literature review part of my paper already...

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COVID 19
An Evidenced Based Pape
SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE
DEGREE OF MASTER OF SCIENCE DEGREE IN NURSING
IN THE GRADUATE SCHOOL OF THE
TEXAS WOMAN’S UNIVERSITY
COLLEGE OF NURSING
Byrishia Williams
NURS 5615 K79
Kristin Cove MSN, APRN, FNP-BC
March 26, 2023

COVID 19
The COVID-19 pandemic has had a great influence on the livelihoods of the American people as well as the healthcare providers. At the start of the pandemic, no effective treatment options were available. Instead, preventative measures were implemented, such as social distancing, hand washing, and wearing masks. Two scientists, Weissman and Kariko, later discovered a vaccine to help aid in the prevention of infections. This paper explores the process of treatment of patients against COVID-19. In adults 25 to 50 years old with mild to moderate symptoms of COVID 19 (P), how effective is monoclonal antibody therapy (I) versus antiviral medications (C) at preventing potential mortality (O)? 
Significance of the Problem
Daniel (2020) states that COVID-19 was first reported in Wuhan, China, in December 2019. Over time the condition has progressively led to the infections of more people, and the death rates have progressively risen. Researchers have helped guide The World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) on what is supposed to be done to ensure that the condition is managed. One of the proposed interventions during the start of the pandemic was the maintenance of social distancing which led to the closure of companies, schools and restrictions put on health facilities. This was followed by the provisions to have regular instances of wearing masks. The use of masks was mainly intended to help in the elimination of any exposure to the droplets of the virus causing COVID-19.
All the proposed interventions were being implemented, but the pandemic was still leading to deaths and more infections in the population. With research, BioNTech
ought in the vaccination that could help in boost immunity to ensure that the virus may not strive in the body. Progressively there has been an implementation of other proposed methods that are expected to help improve the capacity of the people to avoid infections.
Monoclonal antibodies are one of several treatment options in helping attack the virus. There are other treatment methods, including the use of antiviral medications, to ensure that the mortality rates due to COVID-19 are reduced. With the use of monoclonal antibody therapy, the goal is to ensure that the cases of hospitalization are reduced, that there will be a reduction in the viral load and that there will be a reduction in the severity of the symptoms of COVID-19 (Su & Lu, 2021). Monoclonal antibody therapy mainly depends on monoclonal antibodies. The monoclonal antibodies are not different from those that are made by the body, and hence they respond naturally to infections. The antibodies help in the detection of the COVID-19 virus and prevent it from attaching. Specifically, the antibody can recognize the spike protein on the outer shell of the COVID-19 virus and ensure that there is an elimination of the capability of the virus to attach and be able to enter the body cells (Bariola et al. 2021). 
Theoretical model
Implementing changes in the healthcare in the healthcare practice such as the proposal for changes to ensure that the patients with COVID-19 symptoms are treated with the use of a monoclonal antibody therapy will call for the use of a framework or theory. The framework that has been selected in this case is the ACE Star model. The model has five stages: discovery research, evidence summary, translation to guidelines, practice integration, and process and outcome evaluation (Indra, 2018).
In the first stage of discovery of research, there is an examination of the issue of COVID-19 and the research that has been done on the treatment of patients suffering from the condition. This includes the need for the determination of the success attained and the alternatives as well as the recommendations that are made by the researchers across the literature. The research will help to provide the information regarding the health condition.
The second stage entails the summary of evidence. This will entail the identification of specific areas that are found to be of importance in the research. This includes the areas on the issue of healthcare concerns faced by the patients and the effects of certain treatment methods.
The third stage will focus on the translation of the findings into guidelines. In this case, the findings that include the implementation of monoclonal antibody therapy will be developed as guidelines that are to be followed in the process of delivery of care to patients with COVID-19.
The fourth stage will be practice integration. In this stage, there is an adoption of the use of monoclonal antibody therapy in the treatment of patients suffering from COVID-19. This will also focus on determining the influence that the issue of COVID-19 has had on the patient and the changes
ought in by the implementation of this therapy.
The fifth stage is the evaluation of the outcome that is attained with the implementation of monoclonal antibody therapy. In this case, there will be an examination of the issue of mortality due to COVID-19 and the changes that have been attained due to monoclonal antibody therapy. The outcome will be useful for determining the recommendations on the necessary treatment measures for patients with symptoms of COVID-19. 
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