For your written assignment, please write 2000 words on the following topic within clinical decision-making and diagnostic theory (50%). Please review the two assigned papers on the use of faecal...

Article Review
Executive Summary
This paper is a critical review of two article based on the use of faecal elastase to diagnose chronic pancreatitis. One study shows that the estimate of faecal elastase 1 is a helpful new tubeless pancreatic function test, according to a research that compared it to previous tests like the secretinpancreozymin test (SPT). While In another study, for severe and moderate exocrine insufficiency, the faecal elastase-1 test has been demonstrated to be quite accurate. In an acute context, the goal of this study was to compare faecal ELAS-1 concentration [FE-1] to clinical criteria for chronicity. Initially it will be summarize if the research followed the principles of STARD and point out any areas where they were not adequately reported or had flaws. Further it will be discussed about the faecal elastase to diagnose chronic pancreatitis and its use in cu
ent clinical practice.
Table of Contents
Executive Summary    2
Introduction    4
STARD diagnostic accuracy framework    4
Article Analysis 1:    4
Article Analysis 2:    6
The faecal elastase to diagnose chronic pancreatitis    7
The use of faecal elastase in cu
ent clinical practice    8
Conclusion    9
References    10
Introduction
This paper is a critical review of two article based on the use of faecal elastase to diagnose chronic pancreatitis. One study shows that the estimate of faecal elastase 1 is a helpful new tubeless pancreatic function test, according to a research that compared it to previous tests like the secretinpancreozymin test (SPT). While In another study, for severe and moderate exocrine insufficiency, the faecal elastase-1 test has been demonstrated to be quite accurate. In an acute context, the goal of this study was to compare faecal ELAS-1 concentration [FE-1] to clinical criteria for chronicity. Initially it will be summarize if the research followed the principles of STARD and point out any areas where they were not adequately reported or had flaws. Further it will be discussed about the faecal elastase to diagnose chronic pancreatitis and its use in cu
ent clinical practice.
STARD diagnostic accuracy framework
Article Analysis 1:
“Using faecal elastase-1 to screen for chronic pancreatitis in patients admitted with acute pancreatitis
Title – The Title goes along with diagnostic accuracy as Patients with acute pancreatitis may also have chronic pancreatitis, which would require co
ect diagnosis to determine the best course of treatment.
Aim - Gold standard tests are frequently intrusive, expensive, and time-consuming, although the faecal elastase-1 assay has been found to be quite reliable for moderate and severe exocrine deficiency. The goal of this study was to compare the concentration of faecal elastase-1 [FE-1] in an acute context to clinical criteria indicating chronicity.
Methodology - [FE-1] was used on individuals who had recently developed epigastric discomfort and had a serum lipase level that was at least three times the upper limit of normal. The presence of particular clinical, pathological, or radiological criteria for chronic pancreatitis determined the clinical diagnosis. Chronic exocrine insufficiency was also indicated by a [FE-1] result of B/200 mg/g. As a result, a 2/2 table was created to compare [FE-1] and clinical diagnosis.
Result - An analysis of the clinical diagnosis of chronic pancreatitis yielded a sensitivity of 79.5 percent, specificity of 98.0 percent, positive predictive value of 96.9%, and negative predictive value of 86.0 percent for the entire sample and then after excluding patients with moderate and severe acute pancreatitis (Ranson score /2). The latter study was predicated on a 200 mg/g exocrine insufficiency threshold.
Discussion – When obtained during a hospital admission for mild acute pancreatitis, [FE-1] is an accurate screening test for underlying chronic exocrine insufficiency.
The goal of this study was to see how effective [FE-1] was as an objective diagnostic tool in a clinical context, rather than comparing it to another pancreatic exocrine function test. It's a first-of-its-kind attempt to detect chronic pancreatitis in acute pancreatitis cases at the time of, or shortly after, the acute episode. The gold standard diagnostic criteria are all well-known characteristics of chronic pancreatic revelations. The use of [FE-1] in incident instances of acute pancreatitis produced unimpressive results for the standard diagnostic indicators. After excluding instances with moderate or severe acute illness, as indicated by Ranson's score, these significantly improved. Transient acinar cell failure or frank parenchymal necrosis can affect exocrine function, and the degree of the impairment co
esponds with the level of necrosis seen on a CT scan.
With a specificity of 98 percent and a positive...